Blond Psyllium and Warfarin

Publication Date: 
Tue, 11/08/2011
By: Alere Staff

Blond psyllium is an herb or soluble gel-forming fiber, where the seed and the outer covering of the seed (husk) are used for a variety of medicinal purposes. It is often used as a laxative, for diarrhea, or irritable bowel syndrome (IBS). Other uses include high cholesterol, high blood pressure, and diabetes.1 Blond psyllium seed husk or seed added to food or as a separate supplement can reduce levels of total cholesterol by 3% to 14%.2

The product is "likely" safe when used orally in doses up to 20 grams per day for up to 6 months.2 Some foods that contain blond psyllium, used as a food thickener, can carry a label that claims these foods, when consumed as part of a low-fat diet, may reduce the risk of heart disease.3

Blond psyllium has a short but important list of drug interactions. Interactions seen with this product have been observed in anti-diabetic drugs, Carbamazepine, Digoxin and Lithium.

The American Herbal Products Association's Botanical Safety Handbook sited interactions with warfarin and suggests reduced warfarin absorption.4

As always, discuss your diet, medications and any herbal supplements with your doctor.

  1. National Institutes of Health. Blond psyllium. Last reviewed - 09/14/2011.
  2. Anderson, J, et. al. Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials. American Journal of Clinical Nutrition, Vol. 71, No. 2, 472-479, February 2000.
  3. FDA Talk Paper. FDA Allows Foods Containing Psyllium To Make Health Claim On Reducing Risk Of Heart Disease. 1998. Available at:
  4. McGuffin, M. American Herbal Products Association's Botanical Safety Handbook. CRC Press LLC. 1997.