Warfarin is used to slow blood clotting and licorice may influence the effectiveness of warfarin. This in turn could increase the chance of a blood clot forming or lead to an increased risk of bleeding. Since the average person does not eat large quantities of licorice, there is a relatively low risk this candy would have an effect on your INR.
There is a component however, in licorice root (cytochrome p450) that does influence the way your body clears warfarin. The potential is there for a slight increase influence of warfarin clearance.1
Like anything else you eat, when you are on warfarin, you need to have a consistent diet. So, first check with your doctor to see how they feel about you eating licorice. If they give you the “ok”, just make sure you eat the same amount of the same kind of licorice every day (black licorice may have a different effect than red).
Remember to test your INR. Regular periodic testing is a key to managing your INR. Every customer’s situation needs to be evaluated individually to determine the optimum testing frequency that will help keep their INR results in range. Your doctor is in the best position to help you achieve and maintain good health.
- 1. Drug Metabolism and Disposition. American Society for Pharmacology and Experimental Therapeutics. 2002. 30(6): 709-715.