Crestor and Warfarin

Crestor®, manufactured by AstraZeneca, is a drug used to help reduce cholesterol levels. Crestor belongs to a group of cholesterol-lowering medicines called statins. Like any prescription drug, Crestor is comprised of a complicated chemical compound that could interact with other drugs.

Approximately 15 million people in the United States take a statin at any given time. According to the Crestor® prescription insert, a "prolonged INR" may occur while taking Crestor in combination with warfarin.1  

As with any medication, always consult with your doctor regarding any interactions.

  1. Crestor package insert. AstraZeneca Pharmaceuticals LP, 2011.
  2. Bottorff M. Safety and Statins: Pharmacologic and Clinical Perspectives. The American Journal of Managed Care. November 2004 vol 10: S030-037.