Ginger and Warfarin

Publication Date: 
Mon, 11/12/2012

Ginger and dietary supplements containing ginger might have some potential to interact with warfarin. Sources suggest that ginger may increase the risk of bleeding in patients taking warfarin. "Patients taking warfarin and ginger supplements concurrently should have their INR checked regularly and be advised to watch for symptoms of bleeding."1

The Natural Medicines Comprehensive Database suggests that side effects may be seen at a daily dose or consumption of 5 or more grams per day.2 Dietary supplements, including ginger, are not regulated by the FDA.

Increasing testing frequency is recommended when making any changes to your diet, medication, etc. Studies have shown that increasing testing frequency with weekly testing of INR improves patient safety and helps keep the drug in its therapeutic effective zone.3,4 Weekly testing was shown to be the most effective testing frequency.3 Medicare and many private/commercial insurance reimburse patients for weekly patient self-testing.5 Go to the Getting Started page or call Alere at 1.800.504.4032 for more information about testing your INR at home.

  1. Heck, A.M., DeWitt B.A., and Lukes A.L. Potential Interactions Between Alternative Therapies and Warfarin.  American Journal of Health-System Pharmacy. 2000. 57,1221-30.
  2. Jellin J.M., et al. (2005). Pharmacist's Letter/Prescriber's Letter of Natural Medicines Comprehensive Database. 7th ed. Stockton, CA: Therapeutic Research Faculty.
  3. Am J Manag Care. 2014;20(3):202-209.
  4. Heneghan C., et al. Self-monitoring of oral anticoagulation: a systematic review and meta-analysis. 2006. Lancet, 367, 404-11.
  5. Center for Medicare and Medicaid Services. Decision Memo for Prothrombin Time (INR) Monitor for Home Anticoagulation Management  (CAG-00087R) [Memorandum]. 2008. Baltimore, MD.