Neurontin® and Warfarin

Publication Date: 
Tue, 03/01/2016
By: Alere Staff

If you suffer from seizures or neuropathy, your doctor may consider giving you a Neurontin®prescription, also known as gabapentin. The Neurontin® medication was originally intended for the treatment of seizures and classified as an anti-convulsant. Later, it was found to help alleviate pain caused by nerve damage. 

Warfarin is a medication classified as an anticoagulant that prolongs the amount of time it takes your blood to clot. This helps prevent blood clots from forming in your veins and arteries. Warfarin is often prescribed to patients that are at a higher risk for developing blood clots in unusual places within these blood vessels.

A Neurontin® Prescription and Warfarin

If you have been given a prescription for the Neurontin® drug and warfarin, studies have shown that both drugs are compatible. There has been little to no drug interaction between these two medications as the Neurontin® drug is excreted through the kidneys. In studies where participants did experience a drug interaction, the interaction was very mild and not fatal.

Everyone metabolizes medication differently. If you are put on these medications and you think you are having a reaction, do not hesitate to tell your doctor. One of the potential dangers of having to take multiple medications is that some of the medications interact with one another. It is important to talk to your doctor(s) about your medication regimen. This is especially important if you see multiple specialists. Always carry a current and accurate list of all of the medications and supplements that you take. Review your medication list at each doctor visit to help prevent any potentially dangerous drug interactions. Whether it’s a mild rash or a rapid heartbeat, keep your doctor informed. Any time you begin a new medication, notify the doctor managing your warfarin therapy as your INR may need to be checked to see what effect, if any, this new medication might have caused.

References:

  1. Pfizer. Medication Guide: Neurontin (Gabapentin). Distributed by Park-Davis, Division of Pfizer, Inc. NY, NY 10017. Revised September 2015. Retrieved from the website:http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.
  2. Bryant, L., MD, et al. Drug Interactions That Matter and How to Manage Them. Developed for the Goodfellow Unit Symposium. 2007. Retrieved from the website:http://www.rnzcgp.org.nz/assets/documents/Publications/JPHC/June-2009/JPHCJune09Insert24WEB.pdf/.
  3. Sayal, KS, et al. Psychotropic Interactions with Warfarin. Acta Psychiatr Scand. 200 Oct; 102(4):250-5. Retrieved from the website: http://www.ncbi.nlm.nih.gov/pubmed/11089724.

Neurontin® is a registered trademark of Pfizer, Inc. Alere is not affiliated or associated with Pfizer, Inc. or the NEURONTIN® trademark.