Mangoes and Warfarin

Publication Date: 
Wed, 03/07/2012
By: Alere Staff

Although most American consider the mango an exotic fruit with tates of peach and pinapple, it originates from Southeast Asia. According to the U.S. Department of Agriculture, the mango first came to the U.S. in 1880 and is considered part of a healthy diet, rich in fruit and vegetables.1

Interactions with warfarin

Consuming large amounts of mango can influence the stability of your International Normalized Ratio (INR) values. The exact mechanism of interaction is unknown but may be related to the vitamin A content.2

A relatively inexpensive, otherwise healthy food, the mango has a history of raising INR values in patients that consume it regularly over time. You should discuss with your doctor before starting or stopping mango as part of your regular diet.

  1. U.S. Department of Agriculture. Oct 2011.
  2. Monterrey-Rodriguez, J. Interaction between warfarin and mango fruit. Ann Pharmacother May 1, 2002. 36:940-941.

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