Information
Clotamin - a multi-vitamin without vitamin K
Saturday, February 07, 2009
PTINR.com Staff
A new multi-vitamin is available without vitamin K
Clotamin™ is a new multivitamin marketed for patients taking anticoagulants such as Coumadin® (warfarin). The product is classified as a dietary supplement. Clotamin™ is manufactured in a good manufacturing practice (GMP) lab, under conditions that have been recognized worldwide for high quality control and superior manufacturing standards.1
Clotamin™is owned and managed by 30 year-old warfarin (Coumadin ®) patient Justin Barch. He developed this product with the goal of offering a multivitamin without vitamin K.
The makers of Clotamin™ claim that it can be taken with medications like warfarin without affecting international normalized ratio (INR) values.1 This claim has not been evaluated by the FDA, and there are no clinical trials to support this statement.
Vitamins C and E are listed in warfarin package labeling as known to influence INR test results in patients taking warfarin.2 Clotamin™ contains 400% of recommended daily allowance for vitamin C and 333% of vitamin E. PTINR.com asked Barch if this was taken into consideration.
“We consulted with a Pharm.D. as well as leading hematologists when developing the formulation for Clotaminä. We gave special attention to the amount of vitamin C and E in Clotamin™. There are reports3 that suggest taking more than 500 mg of vitamin C can have the effect of lowering a patient’s INR. We have an amount well below that in Clotamin™ (240 mg) and given the fact that vitamin C is water soluble you lose much of that during urination. Vitamin E is found in many leafy green vegetables such as spinach and broccoli, we have found many of our customers have limited their consumption of these foods because of their high concentration of vitamin K. For that reason we thought it was important to have 100 iu of vitamin E in Clotaminä. Reports have shown that taking over 400 iu4 of vitamin E may increase a patient’s INR. We recommend that all of our customers speak to their physicians before taking Clotaminä.”
Mr. Barch stated his company is developing several additional multivitamin lines, designed for patients 65 years and older, scheduled to be available later this year.
Clotamin™ is available from the manufacturer. Patients are encouraged to speak with their healthcare professional before starting or stopping any new products,2 including Clotamin™.
References:
Clotamin – A multivitamin without vitamin K . (2009). Retrieved January 26, 2009, from Clotamin Web site: http://clotamin.com/
Bristol-Myers Squibb Company. (2007). Medication Guide for Coumadin Tablets and Coumadin for Injection [Package Insert]. Princeton, NJ: Bristol-Myers Squibb Company.
Harris, J.E. (1995). Interaction of dietary factors with oral anticoagulants: review and applications. Journal of the American Dietetic Association, 95, 580-4.
Corrigan, J., and Marcus F.L. (1974). Coagulopathy associated with vitamin E ingestion. JAMA, 230 (9), 1300-1.