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Angelica herb & Warfarin

Excessive doses of angelica herb and seed can potentiate therapeutic effects and adverse effects of anticoagulants.

Monday, August 1, 2005

PTINR.com Staff

Trouble as a Rugrat, problems in herb form for Angelica.

Angelica herb and seed are used as a diuretic and as a diaphoretic. In food use, angelica her and seed is used in candied products to decorate cakes and pasteries.

Angelica herb and seed contains volatile oil. It contains furocoumarin which consists of angelicin, bergapten, imperatorin, and xanthotoxin which can make the skin more photosensitive. Natural Medicines Database, 2005

Interaction with Anticoagulants

Theoretically, concomitant use with herbs that have antiplatelet/anticoagulant activity might increase the risk of bleeding in some people. Excessive doses of angelica herb and seed can potentiate therapeutic effects and adverse effects of anticoagulants. The Pharmaceutical Press, London 1996

People typically use 1 teaspoon of powdered seeds or leaves in 1 cup boiling water and drink as a tea twice a day. There are no studies to prove or disprove this amount would have an impact on a warfarin (Coumadin ®) patients INR.

Angelica root is used for loss of appetite, gastrointestinal spasms, the feeling of fullness, and flatulence. It is also used to promote menstrual flow, expectorant, diuretic, and cure for the plague. Caution is encouraged in the use of angelica root and patients on warfarin as the root can potentiate anticoagulant and antiplatelet effects. Eur J Drug Metab Pharmacokinet, 1995

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